Acadia Pharmaceuticals (NASDAQ: ACAD) San Diego, US Small molecules for CNS disorders.
	Albireo Gothenburg, Sweden Small molecules for gastrointestinal diseases (AstraZeneca spin out).
	Altus Pharmaceuticals (NASDAQ: ALTU) Boston, US Protein therapeutics for metabolic diseases (Vertex spin-out).
	Arakis (acquired by Sosei, TSE4565) Oxford, UK Reprofiled molecules for inflammatory and respiratory diseases.
	Ark Therapeutics (LSE: AKT) London, UK Gene therapy for oncology and haematology.
	ARYx Therapeutics (NASDAQ: ARYX) San Francisco, US Safer drugs through retrometabolic engineering.
	Atani  Tokyo, Japan Developing western drugs for the Japanese market.
	Avant Immunotherapeutics (NASDAQ: AVAN) Boston, US Small molecules for the manipulation of the immune system.
	Cerimon Pharmaceuticals  San Francisco, US Therapies for pain, autoimmune and inflammatory disease.
	Chroma Therapeutics  Oxford, UK Small molecules for oncology and inflammation.
	Contec Medical Israel Medical imaging device for diagnosis and surgery.
	DeveloGen Goettingen, Germany Peptides and small molecules for metabolic diseases.
	DrugAbuse Sciences (acquired by Elbion) Paris, France Small molecules for the treatment of addictions.
	Idenix (NASDAQ: IDIX) Boston, US Small molecules for Hepatitis B and C.
	Immgenics (acquired by Abgenix - now Amgen NASDAQ: AMGN) Vancouver, Canada Antibody selection technology.
	Intercell (VSE: ICLL) Vienna, Austria Vaccines for bacterial and viral infections.
	Morphochem (acquired by Biovertis) Munich, Germany Small molecule anti-infectives and anti-coagulants.
	Nabriva Therapeutics Vienna, Austria Small molecules for bacterial infections (Sandoz spin-out).
	OmniSonics Medical Technologies Boston, US Device for clearance of occluded blood vessels.
	Paratek Pharmaceuticals Boston, US Small molecules for bacterial infections.
	Pharmion (acquired by Celgene, NASDAQ: CELG) Boulder, US Small molecules for oncology and haematology.
	Phenomix  San Diego, US Small molecules for Type 2 diabetes and Hepatitis C.
	Sequenom (NASDAQ: SQNM) San Diego, US Diagnostics for rapid genetic analysis.
	Targacept (NASDAQ: TRGT) Winston-Salem, US Small molecules for CNS conditions.
	Viacell (acquired by PerkinElmer, NYSE: PKI)  Boston, US Cord blood banking and cell therapies.
	Weston Medical Stradbroke, UK Needle free drug delivery.
	Zosano Pharma (formerly The Macroflux Corporation) San Francisco, US Transdermal drug delivery technology (Alza/J&J spin-out).